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Recent findings further clarify this mechanism by identifying a role for eukaryotic initiation factor 4a3 (eIF4a3) in the selective recognition of SECIS element subsequences that differ among various Sec transcripts (49)

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The clinical implication of our findings is to use TdGSH to prevent progressive loss of β-cell mass in diabetic patients, who have more glycaemic variabilities because of the vicious metabolic memory obtained from the disease, and to block the development of diabetic complications