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In COVID-19, the serine/threonine kinase mTOR (mechanistic Target of Rapamycin) pathways may offer valuable targets to control cell injury, oxidative stress, and the onset of hyperinflammation 82

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Protein–protein interaction network analysis highlights TNF and AKT1 as central regulatory nodes, suggesting that Tripterygium may modulate key inflammatory and fibrotic signaling pathways (217)