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60 On the other hand, some reports did not show correlation between well-known risk factors such as sex, BMI, diabetes mellitus, alcohol consumption, and preexisting peripheral neuropathy
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In the absence of exogenously supplied vitamin B12, MetE will be the only transmethylase of methionine biosynthesis, making metE an essential gene for methionine biosynthesis ( Since the MetE protein is ubiquitous among bacteria, as it has a pivotal part in the methionine metabolic pathway, to select mAbs recognizing the specific region of Mtb MetE, we produced both the full-length recombinant MetE and its N-terminal fragment, whose sequence is more conserved among mycobacteria